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Ancient stone ruins of Machu Picchu sit on a lush green mountain ridge, surrounded by steep, forested peaks under a blue sky—a travel highlight and iconic wonder of South America.

Highlights of South America

  • 50 Days
  • 49 Nights
  • Get Custom Pricing
  • Customizable & Combinable
South America travel content reviewed by Juergen Keller, Co-Founder & CEO
Several waterfalls cascade down a rocky, green-covered cliff into a misty river below, where a small boat with people inside approaches the base of the falls—one of South America's natural highlights for travel and adventure. Lush foliage surrounds the scene.
Jagged red mountains with sharp ridges are illuminated by soft light under a purple sky. The full moon rises above the peaks, showcasing one of South America's travel highlights, with distant mountains visible in the background.
A person in a red jacket stands on a vast, reflective salt flat in South America under a bright blue sky filled with clouds, creating a mirror-like effect with distant mountains—one of the travel highlights of the region.
A cable car travels toward Sugarloaf Mountain, a tall granite peak rising above lush greenery and a scenic coastline at sunset—an unforgettable highlight of any Brazil tour in Rio de Janeiro.
A cobblestone street lined with colorful colonial buildings and a church tower, lit by streetlights at dusk in Pelourinho, Salvador, Brazil. People and cars fill this vibrant scene on the historic Coast of the Conquerors.
A man in a suit and a woman in a black dress with patterned tights dance passionately outdoors at sunset, with a bridge and cityscape highlighting the vibrant charm of South America in the background.
  • 50 Days
  • 49 Nights
  • Get Custom Pricing
  • Customizable & Combinable

*Example by 4 travelers in 4★ accommodation, low season. Flights priced separately. Get a quote for 1 to 99+ below

Summary - Highlights of South America

The Complete South America - ALL the Highlights!

We’ve put together our ultimate South America itinerary – it’s an extensive list, so be prepared for quite an adventure! If you’ve got 6 weeks to spare, this is the perfect itinerary for you to see all the most important highlights of South America. But if you can’t quite handle a 50 day vacation, don’t fret! This itinerary is just an example of what we can offer; you can customize it to meet your trip plans perfectly.

First we’ll take you on a journey through Peru, to learn about the great Inca empire that thrived here just a few hundred years ago. Continue into Bolivia to see the colorful landscapes and traditional cities of this landlocked country. Then venture into Chile, starting in the Atacama Desert, and make your way towards the central coast. Then cross the Andes into Argentina, where you’ll spend some time in Buenos Aires and then head to the northern tip of Argentina, where the Iguassu Waterfalls pours over the border with Brazil. Once in Brazil, spend some time in São Paulo and Rio de Janeiro. Then delve into the historic gold mining region of Brazil. Finish in Salvador da Bahia, the original capital of Brazil and one of the oldest cities in South America.

After 6 weeks of traveling, you’ll have crossed destinations like Machu Picchu, Buenos Aires, the Iguassu Falls, and Rio de Janeiro off your bucket list!

Highlights

  • Incas: Machu Picchu, Cusco, Sacred Valley
  • Wine tasting
  • Lake Crossing Through The Andes
  • South America main cities: Buenos Aires, Rio de Janeiro, Santiago
  • Brazilian & Argentine sides of Iguassu Falls

Included

  • All 49-Nights accommodations
  • All breakfasts & other meals as mentioned in the itinerary
  • 1 dinner with tango show
  • All tours, transfers and entrance fees
  • First class train transportation Cuzco-Puno
  • Tango lessons
  • English-speaking guides

Sample Itinerary

A smiling couple takes a selfie outdoors on their South America Tour, surrounded by colorful buildings and festive decorations. The man wears a hat and green tank top; the woman wears a yellow dress. Two church towers rise in the background.

First explore the culture of the Incas as you travel to Machu Picchu and Cuzco, the great cities of Lima and La Paz in Bolivia. On Lake Titicaca the floating islands await you on this excursion back in time! The second part is from the Bolivian Capital to the wonders of the Atacama Desert! Astounding contrasts as you journey from La Paz to the crystaline Chilean coastal Oasis of Arica, then into the beautifully fascinating Atacama Desert.

Visit Chile's natural wonders: Santiago de Chile a Mediterranean coast, rolling hills, volcanoes and the highest mountain range in the Western Hemisphere, glacial lakes, European traditions and a heaven for lovers of excellent wines and incredible food. Then the Paris of South America, Buenos Aires. Enjoy sights, sounds, shopping in Buenos Aires, and learn to dance Tango in this beautiful city. We show you both the Argentine and Brazilian sides of the majestic Iguassu Falls.

Take an unforgettable railway journey over the jutting Atlantic Rainforest Mountains, and view a mix of landscapes through southern Brazil on this special introduction into a fascinating land! The contrasts of Brazil become evident as you travel from natural wonders through high-tech farmlands to the industrial megalopolis of São Paulo. From marvelous Rio de Janeiro you are never far away from the best beaches Brazil has to offer.

Discover where the gold originated to build Europe's great palaces and churches. And discover a few treasures along the way. The Route of Gold rambles along rugged mountains from the beautifully preserved colonial gold mining towns of Ouro Preto and São João del Rei to the ancient seaport of Paraty. This bounty of gold provided the wealth to build the royal colonial seat of Rio de Janeiro as well as the Old World capital, Lisbon. The richest deposits of gold ever found in the Americas even financed England's Industrial Revolution!

Home to one of the most ethnically diverse populations on earth, Brazil mixes Old World charm, new world vitality and African rhythms. Many nations have made a claim to Brazil's soul. Today, these influences spice everyday life, from the most African city in the Americas - Salvador to the former Dutch colonies in Recife.

Aerial view of Rio de Janeiro, a South America travel highlight, featuring the Christ the Redeemer statue atop a hill with the city, coastline, and Sugarloaf Mountain framed under a blue sky.
Highlights of South America
  • 50 Days
  • 49 Nights
  • Get Custom Pricing
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The image shows the Ruins of St. Pauls in Macau, with ornate, symmetrical garden hedges leading up to the historic stone facade under a cloudy sky—a perfect highlight for personalized tours in the city.

Michael and Bonnie Escobedo

"The price was reasonable. We would us this travel service again...."
A traditional reed boat floats on blue water near reed huts with colorful red and yellow roofs, under a blue sky. The scene’s exceptional organization is evident in the neatly lined tall grasses along the water’s edge.

Anna K.

"All transfers were on time, all hotels (I picked a mix of 3* and 4*) were good, all guides were friendly, knowledgeable and spoke good English...."
Colorful colonial buildings line a cobblestone street under a bright blue sky with fluffy clouds; a historic church with a clock tower stands prominently in the center, where visitors enjoy excellent service and competitive rates nearby.

Paul

"Great holiday planned..."
A large white cruise ship is sailing on calm blue water under a clear sky. With multiple decks and glass windows, the ship offers excellent service as people enjoy the view from the top deck.

Ronald Lindsey

"So far the booking process has been fabulous...."
Desert landscape at sunset with two distant mountains, a pale sky, and a bright full moon above the horizon—evoking the magic of a trip across Chile or Argentina, where warm, golden hues bathe the breathtaking scene.

Jose Ramon

"We got a very good support from the travel agency to organize the tour...."
Ancient stone ruins of Machu Picchu sit among green terraces with a tall, steep mountain in the background and vibrant red flowers in the foreground, offering amazing views that captivate every visitor.

Stewart Luckman

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Two men wearing headsets smile at the camera while sitting in the front seats of a small aircraft—just another adventure with SouthAmerica.travel. A woman is visible in the back seat between them, ready for more travel recommendations.

Kent and Svend Nielsen

"I have to recommend SouthAmerica.travel to any one that is taking a tour to Peru or South America...."
Four llamas graze near the red waters of a salt lake, with mountains and a blue sky with thin clouds in the background—perfect for travelers seeking upgraded accommodation at competitive pricing.

Siegfried Von Brandt

"This is our second trip to South America and I wanted to see some places we had not seen yet. So we decided on Peru and Bolivia...."
A family of four walks hand in hand along a sandy beach, with blue ocean waves and a clear sky in the background—an experience you'd recommend to a friend.

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"Our experience working with SouthAmerica.travel has been outstanding...."
Close-up of a giant tortoise’s front leg and part of its shell as it moves across dry, brown soil—an unforgettable wildlife experience.

Serta Blacksmith

"Touring the Galapagos Islands and Machu Picchu..."

Estimated Tour Price Without Flights

Prices vary according to several factors including: season, number of people traveling, shared vs private excursions, when you book and rooming arrangements. These are from prices based on low season.

We can customize anything for any time of year! Contact us for an exact quote for your trip.

⭐⭐ - ⭐⭐⭐
Budget
From US
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Per Person
  • Flights quoted separately
⭐⭐⭐⭐
Basic
From US
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Per Person
  • Flights quoted separately
⭐⭐⭐⭐➕
Superior 👍
From US
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Per Person
  • Flights quoted separately
⭐⭐⭐⭐⭐
Deluxe
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately

*Budget generally includes excursions in group, Superior & Deluxe private excursions, & Basic is a best mix (varies by itinerary & excurion)

Note: ALL itineraries are 100% customizable to create your perfect trip!

⭐⭐ - ⭐⭐⭐
Budget
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately
⭐⭐⭐⭐
Basic
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately
⭐⭐⭐⭐➕
Superior 👍
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately
⭐⭐⭐⭐⭐
Deluxe
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately

*Budget generally includes excursions in group, Superior & Deluxe private excursions, & Basic is a best mix (varies by itinerary & excurion)

Note: ALL itineraries are 100% customizable to create your perfect trip!

⭐⭐ - ⭐⭐⭐
Budget
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately
⭐⭐⭐⭐
Basic
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately
⭐⭐⭐⭐➕
Superior 👍
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately
⭐⭐⭐⭐⭐
Deluxe
From US
Call for Custom Pricing
Per Person
  • Flights quoted separately

*Budget generally includes excursions in group, Superior & Deluxe private excursions, & Basic is a best mix (varies by itinerary & excurion)

Note: ALL itineraries are 100% customizable to create your perfect trip!

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