+1 (888) 900-5060
+1 (888) 900-5060
A woman with a backpack hikes along a grassy trail overlooking a turquoise lake and snow-capped mountains—an unforgettable scene from Argentina and Chile tours under a clear blue sky.
Experts in Tailor-Made

Argentina & Chile Combination Trips

Explore South America Tours
FREE South America Travel Guide
South America Travel Info
Let's Plan Your South America Trip
Customize!
20+ Years Designing South America Tours

Argentina and Chile tours are easy to combine, thanks to the long shared border that connects many of South America’s most iconic landscapes. Travelers can explore the vibrant capitals of Buenos Aires and Santiago, discover the wineries of Mendoza and the Chilean Lake District, or journey south into Patagonia for glaciers, granite peaks, and incredible hiking. Whether you’re interested in wine, culture, nature, or adventure, Argentina and Chile pair perfectly in one seamless itinerary.

We offer several combination tours—and you can also build your own customized itinerary. From Patagonia cruises to wine routes, national parks, and cross-Andes journeys, there is an Argentina and Chile trip suited for every travel style.

Custom Argentina & Chile Itineraries

Our Argentina and Chile combination tours are fully customizable. Create a trip that blends Andean scenery, wine regions, glaciers, deserts, and vibrant cities. Popular routes include crossing the Andes between Mendoza and Santiago, pairing El Calafate with Torres del Paine, or combining Buenos Aires with the Atacama Desert. Our Travel Experts tailor each itinerary to your interests, pace, and preferred travel dates.

20+ years designing custom Argentina & Chile itineraries

Prefer to focus on one country in depth? Browse all of our Argentina tours or Chile tours to see everything each destination offers on its own.

Argentina & Chile Combination Itineraries

  • A serene landscape with a salt flat and shallow water reflecting distant pink-hued mountains under a clear blue sky. Perfect for Chile travel, this peaceful scene features textured salt formations in the foreground—one of the hidden highlights of Chile.

    The Highlights of Chile

    • 14 Days
    • 13 Nights
    • From US $6160
    Map of a travel route in South America highlighting Chile attractions, with flights and excursions from Santiago to Easter Island, Punta Arenas, and San Pedro de Atacama. Overnight stays and city tours are marked; an inset map shows global location.
    Chile • Patagonia • Santiago • Torres del Paine
  • A bright yellow colonial church with two towers and a detailed baroque entrance stands in a sunlit plaza in South America, with people walking and pigeons near a central fountain under a blue sky—one of the region’s lesser-known world wonders.

    World Wonders of South America

    • 11 Days
    • 10 Nights
    • From US $3228
    A map of South America highlights a travel route from Lima to Rio de Janeiro, featuring World Wonders like Machu Picchu, with stops in Sacred Valley, Cuzco, and Foz do Iguassu. Icons show overnight stays and excursions along the way.
    Brazil • Bolivia • Peru • South America • Multi-Country • Iguazu Falls • Lima • Cusco • Machu Picchu
  • A wooden cart rests in a field of blooming lupines, with green trees, a lake, and the snow-capped mountains of Patagonia rising in the background—an idyllic scene reminiscent of estancias beneath a partly cloudy sky.
    Popular

    Patagonia Glaciers & Estancias Adventure

    • 5 Days
    • 4 Nights
    • From US $1793
    Map of southern Argentina and Chile in Patagonia showing travel routes between El Calafate, El Chaltén, and Los Glaciares. Icons indicate overnights, estancias, and glacier excursions. Inset map highlights the region’s location in South America.
    Cave of the Hands • Perito Moreno Glacier • Argentina • South America • Buenos Aires • El Calafate • Patagonia • Los Glaciares National Park
  • Aerial view of a city with a park-lined avenue leading to a domed landmark at sunset, surrounded by densely packed buildings under a colorful sky—a scene reminiscent of the Tucuman-Buenos Aires Railway journey.

    The Rhythm of Buenos Aires & Uruguay

    • 8 Days
    • 7 Nights
    • From US $1984
    A map showing a travel route between Buenos Aires, Argentina, and Uruguay’s Montevideo, with stops at Colonia and El Tigre. Icons mark overnights and excursions, while an inset highlights the vibrant rhythm of this South American region.
    Argentina • Uruguay • South America • Multi-Country • Buenos Aires • Patagonia • Montevideo • Punta del Este
  • Three guanacos stand in a grassy field with mountains in the background under a blue sky, showcasing the natural beauty often experienced on Southern Patagonia tours.

    Southern Patagonia at Your Fingertips

    • 8 Days
    • 7 Nights
    • From US $3407
    Map of southern Chile highlighting a Patagonia travel route from Punta Arenas to Puerto Natales, Seno Otway, Balmaceda Glacier, and Torres del Paine. Inset shows Southern Patagonia’s location in South America. Circles mark stops; lines indicate excursions and overnights.
    Cave of the Hands • Chile • South America • Patagonia • Santiago • Torres del Paine
  • Aerial view of a cityscape with a tall clock tower in a park, large historic railway station behind it, green trees, and glimpses of lakes, people, and city buildings extending into the distance under a partly cloudy sky.
    Popular

    Tango & Nature: Buenos Aires, Iguazú & Perito Moreno

    • 8 Days
    • 7 Nights
    • From US $2275
    Iguazu Falls • Perito Moreno Glacier • Argentina • Buenos Aires • El Calafate • Patagonia
  • Snow-capped jagged mountains rise behind a rocky foreground and a turquoise lake near El Chalten, under a bright blue sky with scattered clouds—a breathtaking view on any Patagonia Eco Tour.

    El Calafate & El Chalten Patagonia Eco Tour

    • 7 Days
    • 6 Nights
    • From US $1916
    Map of southern Argentina highlighting Los Glaciares National Park. Key locations include El Calafate and El Chaltén, with icons for overnights, excursions, and Patagonia Eco Tour routes. Inset map shows Argentina’s location.
    Argentina • South America • Buenos Aires • El Calafate • Patagonia • Los Glaciares National Park
  • A large white building with towers and arches stands behind a green vineyard, typical of wineries in Chile, with tall trees and mountains in the background under a partly cloudy sky.

    Wineries of Chile, Argentina, Uruguay and Brazil

    • 12 Days
    • 11 Nights
    • From US $3955
    Map of southern South America highlighting Chile, Argentina, Uruguay, and Brazil. Travel route marked by planes and lines connects cities, with icons for overnights, excursions, and wineries. Inset map shows the region’s location.
    Argentina • Brazil • Chile • Uruguay • South America • Buenos Aires • Mendoza • Rio de Janeiro • Santiago
  • Aerial view of large, powerful waterfalls cascading over cliffs surrounded by lush green forest, with mist rising from the water and a wide river flowing through the jungle landscape—nature’s beauty rivaling pristine beaches and tranquil lakes.
    Popular

    Argentina for True Explorers

    • 15 Days
    • 14 Nights
    • From US $4390
    Argentina • Buenos Aires • El Calafate • Ushuaia • Iguazu Falls
  • Floating ice chunks cover a cold body of water, with a large glacier and rugged, snow-dusted mountains in the background—capturing the breathtaking scenery of a Patagonia Glaciers Cruise under a partly cloudy sky.
    Popular

    Patagonia Glaciers Cruise and Chile Tour

    • 6 Days
    • 5 Nights
    • Get Custom Pricing
    Map of southern South America showing a Patagonia Glaciers Cruise travel route from Chile to Argentina, with stops at Balmaceda, Puerto Chacabuco, San Rafael Glacier, Río Mayo, Perito Moreno, and Comodoro Rivadavia. Insets highlight the region.
    Chile • Patagonia
  • Scenic view of a blue lake surrounded by lush green forests, yellow wildflowers in the foreground, and distant snow-capped mountains beneath a partly cloudy blue sky—an unforgettable highlight of Argentina travel.

    Very Best of Argentina

    • 13 Days
    • 12 Nights
    • From US $3782
    A map of Argentina highlights the best of Argentina travel routes connecting Buenos Aires, Iguassu Falls, Mendoza, Puerto Madryn, Bariloche, El Calafate, and Ushuaia, with icons for flights, overnights, and optional destinations.
    Argentina • Buenos Aires • Bariloche • El Calafate • Ushuaia
  • White, Gaudí-inspired Casapueblo building with curved walls and towers overlooks the blue sea in Punta Ballena, Uruguay—a stunning stop on any coast tour. A tree and stone path are in the foreground under a clear sky.

    Coast to Coast Tour

    • 37 Days
    • 36 Nights
    • From US $18887
    A map of South America showing a Coast to Coast Tour route through Peru, Bolivia, Argentina, and Uruguay. Cities, excursions, overnights, flight and ship paths, and country borders are labeled. An inset map shows the region’s global location.
    Multi-Country • Lima • Cusco • Machu Picchu • Lake Titicaca • La Paz • Salar de Uyuni • Argentina • Bolivia • Peru • Uruguay • South America • Buenos Aires • Iguazu Falls • Salta • Quebrada de Humahuaca
Load More Tours

Create Your Own Custom Tour

Click or Tap your preferences: Destinations & Activities. Be as specific or general as you like – or click Help Me Decide! We’ll spice it with hidden gems & personal tips to create your perfect trip. Need assistance? Contact an expert at +1 (888) 900-5060

Step 1 of 6 - Destinations

Choose Destinations
Destinations
Amazon Interests
Argentina Interests
Bolivia Interests
Brazil Interests
Chile Interests
Colombia & Panama Interests
Ecuador & Galápagos Interests
Paraguay & Uruguay Interests
Patagonia & Antarctica Interests
Peru & Machu Picchu Interests
Guianas Interests
Choose Interests
Get to Know South America and...

Plan Your South America Trip

Get to Know Us

Why Plan Your Journey with Us

South America travel content reviewed by Juergen Keller, Co-Founder & CEO
A vibrant collage highlighting south america tours: a woman with a llama, Rio de Janeiro’s Christ the Redeemer, a boat on turquoise Patagonian waters, Iguazu Falls, and two smiling people leaning from a green train.
Rated 4.5/5 stars based on 701 customer reviews and custom tour testimonials.
With decades of experience crafting journeys across South America, our team combines local expertise, trusted partnerships, and personalized planning to design unforgettable trips. From your first conversation to your return home, we handle the details so you can travel with confidence.
We take care of ALL the details
Customized tours made just for you
Choice of private or group excursions
Superior Hotel Choices
24/7 phone support travel worry free
We are THE South America experts

South America Travel Info

Planning a trip to South America? Explore essential travel info including via requirements, safety tips, weather, money, and more so you can focus on designing the perfect adventure!

Icon
South America Hotels & Resorts
Icon
South America Articles
Icon
South America Staying Healthy
Icon
Internet & Calling in South America
Icon
South America Travel Insurance
Icon
South America Packing List
Icon
Money in South America
Icon
South America Visa Requirements
Icon
South America Flights
Icon
Weather in South America
Icon
Languages of South America
Icon
South America Food & Drink
Icon
Safety in South America
Your Experts in South America!

Let’s Design Your Perfect South America Trip

Four people work at standing desks with headsets and computers in a bright office. A colorful “SouthAmerica.travel” banner and destination photos are displayed in the background.
We Love to Talk About South America Trip Ideas!

Thinking of traveling to South America? We take your South American travel dream and make it a reality. Every fully custom South America trip is planned by your own expert personal Travel Consultant.

"*" indicates required fields

This field is for validation purposes and should be left unchanged.
Full Name

We ❤️ to talk! A brief chat with your personal Travel Consultant helps us create your perfect trip!

South America Travel Guide PDF Cover Page.

South America Travel Guide

Our favorite South America tour ideas featuring the best destinations & activities designed to inspire…

Get your FREE South America Guide Now!

This field is hidden when viewing the form
Name(Required)
Apply