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A boat moves across the wide Amazon River at sunset, leaving ripples in the water. The sky is a gradient of blue and orange, with scattered clouds and the boat’s lights reflecting on the surface—a scene from unforgettable Amazon River cruises.
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Amazon River Cruises

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On our best Amazon River Cruises, explore the Amazon Rainforest and the mighty river itself. The Amazon River runs from Peruvian Andes, north to the border with Colombia, then east through Brazil to Belem on Brazil’s Atlantic coast. In Brazil, Manaus is the main city for Brazil Amazon cruises, which will take you up the Rio Solimoes or the Rio Negro. In Peru, the main city for departing on a Peru Amazon Cruise is Iquitos in the north-east of the country and the world’s largest city that cannot be reached by road. You can also float down the less-traveled tributaries of the Amazon basin in Bolivia and Ecuador. On our Amazon river tours, guests will be able to venture further into the Amazon and spot incredible wildlife and learn about the indigenous communities. There are several Amazon cruises to choose from, and we can fully-customize any cruise so that it best suits you.

Top 9 Amazon River Cruises

  • Modern suite aboard the M/C Petrel Galapagos Cruise with wood floors, a bed with white linens, a seating area with two white chairs, a black chair, a glass table with drinks and snacks, and a large window showcasing ocean views.

    M/C Petrel Catamaran Galapagos Cruise

    • Get Custom Pricing
    Petrel Galapagos Island Cruise | Galapagos Cruises. 8 day, 5 day, or 4-day Galapagos Island Cruises, enjoy multiple islands, meet local wildlife, and experience unique landscapes only the Galapagos can offer. From Land Excursions, Snorkeling, Charles Darwin Research Station, & Island Explorations.
  • A group of people stand on the bow of a cruise ship navigating icy Antarctic waters near Ushuaia, surrounded by floating ice and snow-capped mountains, reflecting off the calm, blue water under a clear sky.

    Best Antarctica Ushuaia Cruise

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    Best Antarctica Ushuaia Cruise | Ushuaia Shetland Cruise. Enjoy a 10, 11 or 12 days Antarctica cruise from Ushuaia through the South Shetland Islands to the Antarctic Peninsula. Book a cabin aboard the Best Antarctica Ushuaia cruise and have the adventure of a lifetime!
  • A blue and white ship, the Plancius, is anchored on calm water with snowy mountains in the background under a partly cloudy sky, capturing the serene beauty of an Antarctica Cruise departing from Ushuaia.

    Ushuaia to Antarctica Cruise on the Plancius

    • 11 Days
    • 10 Nights
    • Get Custom Pricing
    Roraima Trail Trek to Mount Roraima Venezuela Tour & Fully-Custom Hikes along the Roraima Trail to Mount Roraima. We offer the best Roraima Trail Trek Tours to Venezuela. Mount Roraima sits in beautiful Canaima National Park. Spend 6 days trekking to the top of Mount Roraima.
  • A white cruise ship sails on calm blue water near a lush, green and yellow coastal landscape of the Galapagos Islands, with sparse trees and distant mountains under a clear sky—the perfect scene for a memorable Galapagos cruise.

    Galapagos Islands Cruise on the Galapagos Legend

    • Get Custom Pricing
    Board the Legend for 3, 4 or 7 night unforgettable Galapagos Islands cruise. Discover the unique wildlife studied by Charles Darwin.
  • Floating ice chunks cover a cold body of water, with a large glacier and rugged, snow-dusted mountains in the background—capturing the breathtaking scenery of a Patagonia Glaciers Cruise under a partly cloudy sky.

    Patagonia Glaciers Cruise and Chile Tour

    • 6 Days
    • 5 Nights
    • Get Custom Pricing
    Taste and see delicious Caribbean and Andean Colombian cuisine, including coffee, brandy, and seafood, on this Colombia gourmet tour.
  • Two white yachts float on calm water at sunrise or sunset, the sun low on the horizon and a rocky island visible in the background. Experience serene beauty with Coral Cruises in the Galapagos under a partly cloudy sky.

    Galapagos Island Coral Cruises

    • Get Custom Pricing
    Board the Coral I or II to experience the unique Galapagos Islands on an all-inclusive cruise. 3 different itineraries to explore the islands.
  • Three people in warm jackets and hats ride a small inflatable boat through icy blue water, snow-covered mountains, and floating icebergs—a snapshot from an unforgettable Antarctic expedition under a clear sky.

    Antarctica XXI Cruise

    • Get Custom Pricing
    Discover the white landscapes and vast wildlife including penguins, seals, and whales with SouthAmerica.travel
  • A scenic view of a small, sandy island surrounded by blue ocean waters, rocky shores, and lush vegetation under a partly cloudy sunset sky—perfect for a Galapagos cruise. In the distance, a larger landmass is visible.

    Galapagos Cruise and Machu Picchu

    • 12 Days
    • 11 Nights
    • From US $6308
    Explore Colombia’s coffee region & taste the world’s best coffee. See the Andes Mountains & volcanoes & stay on a real Colombian coffee farm.
  • A train with red and black cars, famously known as the Devil's Nose Train, travels along winding tracks on a steep, rocky mountainside covered in sparse vegetation near Quito—a highlight of any Ecuador tour.

    Luxury Galapagos Cruise & Ecuador Trains

    • 14 Days
    • 13 Nights
    • Get Custom Pricing
    Explore San Cristobal, Isabela and Santa Cruz Island in 5 jam-packed days. Discover wildlife of the Galapagos with SouthAmerica.travel
  • A marine iguana with rough, dark scales stands on a sandy Galapagos beach dotted with seaweed, blue ocean waves rolling in, and a distant shoreline under a sunny sky—an iconic scene on any Galapagos tour.

    Cruise the Galapagos and Tour Colonial Quito

    • 8 Days
    • 7 Nights
    • Get Custom Pricing
    Tour the highlights of Colombia on the exclusive trip. Visit the capital Bogota, colonial Villa de Leyva & archaeological San Agustin.
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Why Plan Your Journey with Us

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With decades of experience crafting journeys across South America, our team combines local expertise, trusted partnerships, and personalized planning to design unforgettable trips. From your first conversation to your return home, we handle the details so you can travel with confidence.
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